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Hypoglycemic effect of commercially prepared supplements of Lagerstroemia speciosa in hyperglycemic albino mice induced with a diet rich in high fructose corn syrup.


Christian Jerome S. Carreon,
Dr. Ricardo R. Santos,
Dr. Roberto  Z. Yuseco,
Dr. Ricky V. Pinpin,
Kristel Marie P. Anunciacion,
Jennifer T. Bonifacio,
Opal Anne A. Balajadia,
Tristan Angelo M. Calaquian,
Aleth S. Cruz,
Sunil Basnet,
Samridhi Dawadi,
BIjay Dali,
Ainah Pamela D. Cunanan,
Carleen Nicole D. Araos,
Olivia Victoriano M. Calaguas,
Chungda Chhumare,
Joanna Marie B. Balingit,
Justin Ral D. David,
Rosa Lauren D. Cunanan,
Prajwol Bhurtel,
Aris Miguel D. David

Publication Information

Publication Type
Research Report


Lagerstroema speciosa known as "banaba" is traditionally used as a herbal medicine in the Philippines. Although Lagerstroema speciosa has been shown to produce hypoglycemic effects in some mice models of diabetes, there are no reports of the effects of this substance in non - diabetic mice fed with diet rich in monosaccharides. Thus, the study aimed to provide the mice a diet that is consistent with an increased risk of developing type 2 diabetes mellitus, administer herbal supplements and check glucose levels. Herbal plant extract was given to the experimental group. Fasting blood glucose values before and after the 2 weeks period were taken and an oral glucose tolerance test were done to the mice. Statistical analysis showed significant difference between the control (mean = 231.4mg/dl) and the experimental group (mean =173mg/dl) (P < 0.01). The result of the study shows that Lagerstroema speciosa extract has a glucose lowering effect in mice under a high fructose corn syrup diet.



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